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discount viagra Alprostadil can also be injected directly into the penis. A very small needle about the size of those used to inject insulin is used for this purpose, so any pain or discomfort should be minimal. Penile injections can be used alone or in combination with an oral drug. The maximum recommended dose for Viagra (sildenafil), used to treat ED (erectile dysfunction), is 100mg per day. It does have interactions with other medications, so you may want to find out if you are taking any medications that may be interfering with it. Medications for hypertension (high blood pressure) are usually fine to take with it, as far as drug interactions go. Have any of your heart medications been increased, especially ones that are known to cause erectile dysfunction, such as the beta blocker family, Tenormin (atenolol), Lopressor (metoprolol) and others? Do you have any other physical conditions that may be causing it, such as other vascular problems, issues with nerves that send the arousal signal from the brain and spinal cord to the penis (common in diabetes), problems with the structure of the penis or the surrounding tissue, low testosterone, or use of tobacco, alcohol, or illegal drugs? If the medication is losing it's effectiveness for you, you may want to consult your doctor for an alternative. Other medications that are in the same family and work in a similar manner are Cialis (tadalafil) and Levitra (vardenafil), but if one does not work as well for you anymore, another may work better. All three of these medications inhibit an enzyme (PDE-5) that breaks down the substance produced by the penile tissue in response to sexual stimulation, and helps the erection occur. Cialis (tadalafil) is known as the "weekend pill," because it lasts approximately 17 to 36 hours. Levitra (vardenafil) is similar to Viagra (sildenafil), as it lasts about 5 hours (Viagra (sildenafil) lasts about 4 hours), but it is the one that works the fastest.
In addition to human corpus cavernosum smooth muscle, PDE5 is also found in other tissues including platelets, vascular and visceral smooth muscle, and skeletal muscle, brain, heart, liver, kidney, lung, pancreas, prostate, bladder, testis, and seminal vesicle. The inhibition of PDE5 in some of these tissues by sildenafil may be the basis for the enhanced platelet antiaggregatory activity of NO observed in vitro, an inhibition of platelet thrombus formation in vivo and peripheral arterial-venous dilatation in vivo. Cardiovascular Effects [see Contraindications (4.1) and Warnings and Precautions (5.1)] Anti-depressant medication such as:
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